Ziccum enters into evaluation agreement with global pharmaceutical and vaccine company

Stockholm, October 3, 2019. Ziccum AB (publ) (‘Ziccum’) is to conduct an evaluation study with a global healthcare company engaged in researching and developing, vaccines and proteins to combat infectious diseases. The project will explore whether Ziccum’s air-drying capabilities could generate stable, dry-form vaccines for the company. 1-in-5 children worldwide currently do not receive even basic vaccines (WHO), and 1.5 million die every year from vaccine-preventable diseases. 

“We’re very proud to be starting this pilot project for such a prestigious and committed pharma company”, says Ziccum CEO Göran Conradson. “It’s a global company based in Europe who is committed to helping people be healthier by supporting better access and care in more places around the world. If our technology could be a part of that we would of course be delighted.”

“The pilot project collaboration is the second in just months”, Ziccum’s Chairman Fredrik Sjövall points out. “We clearly told the market that our first-year goal as a listed company was to partner on three pilot studies looking at developing stable, dry form vaccines and biologics. We’ve delivered on that promise. This is the second industrial collaboration we have announced in just a couple of months, and we see growing commercial interest in LaminarPaceTM moving forward. The world’s need to be able to deliver vaccines beyond the cold chain, to where they’re really needed, is urgent and growing. We’re convinced that our proprietary LaminarPaceTM technology may come to play an important part”.

LaminarPace enables the air-drying of delicate biologic drugs such as proteins, peptides and vaccines at room temperature, keeping the active ingredient intact. This capability could enable the development of new, stable, dry powder formulations of vaccines and biologic therapies that do not require costly global refrigeration supply chains to be transported and administered coast-effectively to any climate in the world.

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB 

E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99 

About Ziccum 

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets – and open up new ones. Ziccum’s share is traded on Spotlight Stockmarket. www.ziccum.com

The information above was provided for publication on October 3, 2019 (20.00 hours) by Ziccum AB (publ) according to EU Market Abuse Regulations, through the above contact person.

ZICCUM AB Half Year Report Q2 2019

Summary of Half Year Report second quarter 2019: This has been an eventful year for Ziccum.

Summary of Half Year Report, second quarter 2019

2019 has been eventful for Ziccum: We have filed a patent application for an important component in the development of new vaccines, Adenovirus. This has resulted in several industrial players showing new interest in our technology. We also announced that we have entered into a Contract Research agreement with one of these companies, aimed at evaluating LaminarPace ™ in combination with their own project. In the second quarter we also got together groups of leading industrial and academic players to take part in developing dry formulations of many new vaccines and viruses, in the process furthering LaminarPace’s progress towards adapting to large-scale industrial production of biological drugs and vaccines. Consequently we are well on the way to delivering on the targets we set during our share listing – namely carrying out three pilot studies within one year to develop stable, dry vaccines and biological drugs.

April-June 2019

Net sales SEK 0 thousand (2) Net sales SEK 0 thousand (192)

Operating profit SEK -2,296 thousand (-573) Operating profit SEK -3,998 thousand (-728)

Earnings per share before and after dilution SEK -0.38 (-0.24)

January-June 2019

Net sales SEK 0 thousand (192)

Operating profit SEK -3,998 thousand (-728)

Earnings per share before and after dilution SEK -0.67 (-0.32)

Significant events during the reporting period (Jan-Jun) 2019

Ziccum reported on January 10, 2019 that the company filed a patent application for a dry, temperature-stable formulation of Adenovirus, so meeting WHO requirements for CTC status. The dry formulation ("the powder") generated by Ziccum"s technology LaminarPace ™ can be rapidly dissolved back into solution by the addition of sterile water, after which vaccination or treatment can be carried out.

Significant events after the reporting period

  • Ziccum will, on behalf of a vaccine development company, carry out a feasibility study on the development of stable vaccines. At this stage, the preliminary study does not entail any financial compensation, but aims to investigate the compatibility of Ziccum"s air-drying capability and the vaccine company"s new formulation.
  • Otherwise, no significant events have occurred after the reporting period

READ THE WHOLE REPORT HERE

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB
E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones.

This press release has been submitted for publication by the company"s CEO at. 08.00 (CET) on August 21, 2018.

Ziccum AB (publ) to carry out Proof-of-Concept feasibility study for pharma formulation company

(Stockholm July 2, 2019) Ziccum AB (publ) (“Ziccum”) is carrying out an early-stage feasibility study for an innovative pharma company.

The early-stage Proof of Concept study involves no financial exchange, but is to explore the compatibility of Ziccum’s air-drying capabilities with the company’s novel formulation. LaminarPace, Ziccum’s proprietary technology, air dries proteins, peptides and biologics at room temperature into stable, dry-form substances.

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB

E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones.

The information above was provided by Ziccum AB (publ) through the above contact person, for publication on July 2, 2019.

Ziccum receives research grant from Vinnova AB (publ)

Ziccum has received a 200,000 SEK research grant from Vinnova AB (publ). The research grant will be used to evaluate Ziccum"s method of producing vaccines in dry-powder form.

The evaluation will take place in the ‘TESTA Center’ laboratories in Uppsala in premises that comply with BSL2 (Biosafety Level 2) standards, the required standard for collaboration with industrial partners on vaccine development.

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB

E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones.

The information above was provided by Ziccum AB (publ) through the above contact person, for publication on June 28, 2019.

Ziccum AB (publ) Flagging message (regulatory)

(Stockholm May 29, 2019) Ziccum AB (publ) received information on the change in the number of shares related to Inhalation Science AB"s sale of 400,000 shares on May 23, 2019.

Inhalation Science AB had 2 190 000 shares in Ziccum before the sale, corresponding to 36.5% of the capital and votes. After the transaction on May 23, the holding is 29.8%. The flagging message is published when the holding passes below 30% after the change in the number of shares in Ziccum.

PLEASE NOTE: This is an unofficial translation of the original notice, which is in Swedish. In case of discrepancies, the Swedish version shall prevail.

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB

E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones.

The information above was provided by Ziccum AB (publ) through the above contact person, for publication on May 29, 2019.

Report from Ziccum AB (publ) Annual General Meeting, May 20, 2019

(Stockholm, Sweden, May 20, 2019.)  Today, May 20, 2019, the Annual General Meeting was held for Ziccum AB (publ). Below is a summary of the decisions made. All decisions were made with the required majority.

PLEASE NOTE: This is an unofficial translation of the original notice, which is in Swedish. In case of discrepancies, the Swedish version shall prevail.

Dividend

The Annual General Meeting resolved to establish the presented income statement and balance sheet. It was also resolved at the Annual General Meeting that no dividend would be paid for the financial year 2018.

Discharge

The Board of Directors and the President were discharged from liability for the 2018 financial year.

Board, auditor and fees

Ola Chamber, Kristian Kierkegaard, Mattias Münnich and Fredrik Sjövall were re-elected as board members and Mikaela Bruhammar was newly elected. Fredrik Sjövall was re-elected as Chairman of the Board. It was resolved that the fee shall be SEK 150,000 to the Chairman of the Board and SEK 75,000 each to the other Board members.

Ernst & Young AB was elected to the auditing firm. Authorized public accountant Stefan Svensson will be the chief auditor. It was decided that remuneration to the auditor should be paid according to approved invoice.

Authorization for the Board to issue shares, convertibles or warrants

In accordance with the Board"s proposal, the Meeting resolved to authorize the Board of Directors, on one or more occasions before the next Annual General Meeting, with or without deviation from the shareholders" preferential rights, to decide on a new share issue or issue of convertibles or warrants. The issue may be made against cash payment, non-payment or set-off. The number of shares that may be issued, or, upon the issue of convertibles or warrants, additional after conversion or exercise, with the support of the authorization shall be limited to ten (10) percent of the number of shares outstanding at the time of this meeting.

Decision to change the seat

The Meeting resolved to amend the Articles of Association in such a way that the seat of the Board of Directors is changed from Huddinge municipality to the municipality of Lund.

Flemingsberg May 20, 2019

Ziccum AB (publ)

Board of Directors

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB
E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones.

This press release was submitted for publication 20 May, 2019.

Ziccum AB: senior Astra Zeneca vaccine & biopharmaceutical strategist to be new Board member

Few people know the special risks and rewards of working with vaccines and biopharmaceuticals better than Astra Zeneca’s VP Mikaela Bruhammar. From 2012-2015 she led the team that launched and grew Astra Zeneca’s unique inhalable LAIV flu vaccine in Europe and US. Now she will bring her biologics/ vaccine expertise and broad pharma commercial experience to the Board of Ziccum AB. She will be proposed as new Board Member at the company’s Annual General Meeting on May 20.

“The rewards can be great, but the risks can too. Vaccines aren’t like other pharmaceuticals. For some companies they can be scary”. She should know. From 2012 to 2015 Astra Zeneca’s current Vice President of Nordic-Baltic Business Unit in Respiratory, Inflammation and Autoimmune disease (RIA), was the Global Head of Astra Zeneca’s Vaccine Franchise—successfully developing and commercializing Fluenz (Europe) / FluMist (the US), its inhalable Flu vaccine for children.

“The business model for vaccines is significantly different to other pharmaceuticals. Vaccines are heavily policy-driven. They demand a long-term commitment from developers and government—you can’t change or adjust your vaccine programs every other year. The extensive collaboration needed between commercial forces, the WHO and governments is unique. It requires a level of commitment that ‘new-to-vaccines’ pharma companies can find scary. You have to ask yourself ‘can you commit to continue supplying this vaccine for the next 50 years?’”

Bruhammar and her team faced all these challenges, and more serious ones, when commercializing Fluenz. Yet they launched successfully in just three years, an exceptionally short period. How did they ‘achieve the impossible’? And what can it teach Ziccum?

VACCINES: MAKING THE IMPOSSIBLE POSSIBLE

“It’s true we had a really challenging product”, says Bruhammar. “It was a live vaccine, a weakened version of the flu virus itself. Once thawed from its frozen form it only had a shelf life of 16 weeks. So you can imagine the logistics. On paper it was an impossible product to sell. But the thing is it was highly efficacious, highly potent, and it was a needle-free, nasal spray vaccine aimed at kids – who don’t like injections. Plus children are highly infectious carriers of flu in the general population. So if you can successfully immunize your paediatric population you get a powerful knock-on effect on your overall population, in fact you only need to inoculate 30% of children in order to have a population-wide impact. So that was the package of benefits. There was a triple win. For us, the developer; for NGOs and governments; and crucially, for patients. Everyone got a clear win out of it. And because of that, all of a sudden stakeholders were willing to be flexible to get over the 16-week shelf life, for instance the EU regulatory agency agreed to an annual tailor-made approval process for this specific vaccine, a key enabler for the EU launch. And in the UK the NHS trained special vaccinators to administer Fluenz to millions of school-children during 1-2 months every fall.”

WHAT DOES IT TEACH ZICCUM?

 “I see a lot of the same excitement and potential with Ziccum right now as I saw with the Fluenz project back then,” says Bruhammar. “It’s super-exciting to be joining at such an interesting phase. As Fluenz shows, you have to paint the big opportunity in such a way that people get it immediately. I see that connection with Ziccum. You can tell Ziccum’s dry vaccines and biologics story in two sentences and people get it. There’s a momentum that has already built up around Ziccum, and a big picture. Now I want to see that momentum accelerate. And as I said, the triple win—showing clearly how the technology solves key problem for pharma developers, NGOs and governments—and patients, is crucial.

“For example, dry powder formulation solves the cold chain challenge, but how would it be for patients and clinics? For conditions that require multiple administrations many clinics want the patient to self-administer. They don’t want large patient traffic or a logistics chain in-clinic. So a nurse having to reconstitute and rehydrate large batches of dry vaccines back into liquid solution might not be a win for them. But if an autoinjector reconstituted the dry powder back into solution for the patient, in the pen or device, with sterile water behind a seal that remixed the solution with a couple of shakes—then you’re back in the game. And as Fluenz shows, if the solution is a win for everybody people will solve challenges. For large investors, being able to make major cold chain savings could make it well worth solving other challenges. Whilst for big-volume vaccinations like standard flu shots or MMR vaccine (measles, mumps and rubella that most children get at 1 and 3 years), if the clinic knows it has to administer 20 shots in the afternoon, and needs to reconstitute a batch in the morning, that’s still a saving that lets them administer more shots, because the price of the shots is lower, thanks to cold chain costs having been cut drastically. So dry formulation would obviously be a big benefit there. But it’s all about the real clinical setting and what Ziccum’s dry formulation capabilities actually look like in the end reality.  

2000 POTENTIAL PROJECTS

“There are 2000 potential projects Ziccum technology could add value to. Applying Ziccum technology into the context of the real patient journey, making it real for patients and producers, is key to deciding which to prioritize and tackle first. It’s not until we see how the technology fits into the patient’s life and journey that we find the real value drivers and value points.

“A great partnership or collaboration scenario is where everybody wins. So it comes down to priorities. What is the scale we dare to grow to? Do we dare to dream big? The Fluenz case shows that even seemingly ‘impossible’ challenges can be overcome when you can demonstrate clearly how everyone wins. I drove forward commitment to vaccines within a company that was not really focussed on vaccines. It was a pivotal experience for me and gave me really great lessons in how to focus an organisation on vaccines and what to prepare for when moving towards developing vaccines.

“Plus, if we expand the definition of vaccines a little to include let’s say peptides genes or biologics which could be an on- or off- switch for an autoimmune disease say, then the opportunities are even bigger. There are some really promising auto switches for airway inflammation. What if you could switch-off asthma early on or stop COPD progression? For asthma and COPD – which are horrific diseases – these could stop that process, so people would not need to suffocate to death.

“I’m super-passionate about driving business and delivering results. I never hesitate to try, fail and try again. I believe dry formulations have a big part to play in vaccines and biologics, and I think that in inhaled biologics for sure there is a very visible lead or opportunity for the technology. With vaccines—there is currently human commitment from many of the most influential and progressive organizations on the planet. These groups and organisations have their eyes clearly on this, so maybe with their backing we can afford to think and dream bigger. I’m looking forward hugely to this journey.”

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB

E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones.

Ziccum Q1 Report 2019 released

(Stockholm May 9, 2019)  Ziccum AB today releases its Q1 Report for 2019. The Report is now available on the company’s website.

Summary of interim report – first quarter 2019: Successful development of a dry, temperature-stable formulation of Adenovirus resulted in a filed patent application and a significant milestone for Ziccum. Dialogue with potential Customers and partners continue with increased intensity, and an application has been submitted to Horizon 2020 step 2.

January – March 2019

Net sales SEK 0,0 (190)

Operating profit SEK -1,689 thousand (-137)

Earnings per share before and after dilution SEK -0.28 (-0.05)

Significant events during First Quarter 2019

  • Ziccum reported on January 10, 2019 that the company had filed the patent application for Adenovirus with dry and temperature-stable formulation that meets WHO"s CTC status requirements. The dry formulation ("powder") generated by Ziccum"s technology in LaminarPace© is rapidly dissolved when adding sterile water after which vaccination or treatment can be performed.
  • During the first quarter of 2019, we submitted our Phase 2 application for Horizon 2020

For further information please visit www.ziccum.com

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB

E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones.

The information above was provided by Ziccum AB (publ) through the above contact person, for publication on May 9, 2019.

Notice of Annual General Meeting

The shareholders of Ziccum AB (publ) are hereby invited to attend the Annual General Meeting on May 20, 2019 at 14.00 at Hälsovägen 7 in Flemingsberg. Voting rights registration starts at. 13.30, and is cancelled when the meeting opens.

NOTE: This is an unofficial translation of the original notice, which is in Swedish. In case of discrepancies, the Swedish version shall prevail.

Right to participate

The right to participate in the Annual General Meeting has been the one that has been recorded as a shareholder in the share register kept by Euroclear Sweden AB regarding the circumstances on May 14, 2019, and not later than May 14, 2019 2019, to the company, announce its intention to participate in the Annual General Meeting. Application can be made in writing under the address Ziccum AB (publ) c / o Fredersen Advokatbyrå, Turning Torso, 211 15 Malmö or via e-mail to ziccum@fredersen.se. When registering, the name, address, personal or corporate identity number, telephone daytime, and, if applicable, number of assistants (maximum two) must be stated. After registered registration, the notifier will receive a confirmation. If no confirmation is received, the notification has not been done correctly.

Shareholders whose shares are nominee registered, i.e. kept in a custody account, must temporarily register the shares in their own name in the share register kept by Euroclear Sweden AB in order to be able to participate in the meeting. Such registration must be completed no later than May 14, 2019 and should be requested well in advance of that day with the person managing the shares.

Proxy

If shareholders intend to be represented by a proxy, a proxy must be issued for the representative. The authorization must be in writing, signed by the shareholder and dated. If the shareholder is a legal person, a copy of the registration certificate or, if such document does not exist, the corresponding authorization document is attached to the notification. The document must prove the right of the person who signed the authorization to appoint a representative for the legal person. In order to facilitate registration at the AGM, the power of attorney in the original and registration certificate and other authorization documents should be made available to the company at the above address no later than May 14, 2019. If a power of attorney and other authorization documents have not been submitted in advance, the power of attorney in the original and other authorization documents may be presented at the meeting. Proxy forms are available at the company and on the company"s website, www.ziccum.com, and are sent on request to shareholders who state their postal address.

Proposed agenda

1. Opening

2. Election of Chairman of the Meeting

3. Preparation and approval of voting list

4. Election of one or two adjusters to sign the minutes

5. Testing of whether the meeting has been duly convened

6. Approval of the agenda

7. Statement by the CEO

8. Presentation of annual report and audit report

9. Decide on

a) Establishment of income statement and balance sheet

b) Disposition of the Company"s profit or loss according to the established balance sheet

c) Discharge from liability for the board members and the CEO

10. Determination of the number of Board members elected by the AGM and the number of auditors and deputy members

11. Determination of fees for the Board and the auditors

12. Election of Board members, auditors and any deputy auditors

13. Election of Chairman of the Board

14. Resolution to authorize the Board to issue shares, warrants or convertibles

15. Decision to amend the Articles of Association

16. Termination

Motions

Dividend (item 9b)

The Board of Directors proposes that no dividend be paid for the financial year 2018.

Election of chairman of the meeting, board of directors, chairman of the board and auditor and determination of fees (paragraphs 2, 10-13)

Suggested proposals

  • that Fredrik Sjövall is elected chairman of the meeting,
  • that the board shall consist of five members,
  • that an auditor without deputy auditor should be appointed,
  • that board fees shall be SEK 150,000 to the chairman of the board and SEK 75,000 each to the other board members,
  • that audit fees are paid according to approved invoice,
  • the re-election of the board members Ola Chamber, Kristian Kierkegaard, Mattias Münnich and Fredrik Sjövall, and that Mikaela Bruhammar is elected as a new board member,
  • that Fredrik Sjövall is re-elected Chairman of the Board, as well as
  • that Ernst & Young is elected new auditor; Ernst & Young has announced that Authorized Public Accountant Stefan Svensson is intended to be the chief auditor if the meeting appoints Ernst & Young as auditor of the company.

Mikaela Bruhammar, born 1976. For the past 10 years, Mikaela has worked for Astra Zeneca and has many years of experience working with both vaccines and biological drugs, among other things she had a leading role in the commercialization of Astra Zeneca"s influenza vaccine Flumist. Mikaela holds a Master"s degree in molecular biology from Linköping University. Mikaela is independent in relation to the company and to the company"s major shareholders. Mikaela has no shares in Ziccum.

Authorization for the Board to issue shares, convertibles or warrants (item 14)

The Board of Directors proposes that the Annual General Meeting authorizes the Board, on one or more occasions before the next Annual General Meeting, The Board of Directors proposes that the Annual General Meeting authorizes the Board, on one or more occasions before the next Annual General Meeting, with or without deviation from the shareholders" preferential rights, to decide on a new issue of shares or issue of convertibles or warrants. Issues shall be made against cash payment, non-payment or set-off or in other cases on terms referred to in Chapter 2. Section 5, second paragraph, 1-3 and 5 the Swedish Companies Act. The number of shares that may be issued, or, upon the issue of convertibles or warrants, additional after conversion or exercise, with the support of the authorization shall be limited to ten (10) percent of the number of shares outstanding at the time of this meeting. If the Board decides on an issue without preferential rights for the shareholders, the reason should be to be able to broaden the ownership circle, acquire or enable acquisition of working capital, increase liquidity in the share, carry out company acquisitions or acquire or enable acquisition of capital for company acquisitions. When deciding on issues without preferential rights for the shareholders, the subscription price must be market-based at the time of the issue decision.

Decisions pursuant to this paragraph presuppose for their validity that they are assisted by shareholders with at least two-thirds of both the votes cast and the shares represented at the meeting.

Decision to amend the Articles of Association (item 15)

The Board of Directors proposes that the Annual General Meeting resolves to amend the Company"s Articles of Association as follows:

Current wording

§ 2

The Board of Directors shall have its registered office in the municipality of Huddinge.

Proposed wording

§ 2

The Board of Directors shall have its registered office in Lund Municipality.

Decisions pursuant to this paragraph presuppose, for their validity, that they are assisted by shareholders with at least two-thirds of both the votes cast and the shares represented at the general meeting.

Other information

The annual report, the auditor"s report and the complete basis for decision-making will otherwise be available at the company and on the company"s website at least as long before the meeting as follows by law. The documents are sent on request to shareholders who state their postal address. The Board of Directors and the CEO, if any shareholder requests it and the Board considers that this can be done without material damage to the company, provide information at the Annual General Meeting on circumstances that may affect the assessment of a case on the agenda and circumstances that may affect the assessment of the company financial situation.

Processing of personal data

For information on how your personal information is processed see

www.euroclear.com/dam/ESw/Legal/Integritetspolicy-bolagsstammor-svenska.pdf.

Huddinge in April 2019

Ziccum AB (publ)

Board of Directors

For more information about Ziccum, please contact:

Göran Conradson: CEO Ziccum AB

E-mail: conradson@ziccum.com

Mob: +46 709 61 55 99

About Ziccum

Ziccum AB (publ) develops new patented formulations of biological drugs where sensitivity to temperature differences, especially during transportation, currently limits medical and so commercial potential. The company’s patented technology, LaminarPace, develops dry powder formulations of drugs and vaccines that currently only exist in liquid form. By doing so Ziccum can increase the availability of drugs and vaccines in existing markets—and open up new ones. This press release was submitted for publication by the CEO at 08.00 (CET) on 14 November, 2018.

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